When was brucella discovered

S [3] Overview Brucellosis is an ancient disease. Historical Perspective Brucellosis is an ancient disease. In , Sir David Bruce, Scottish physician, isolated gram negative coccobacilli from spleens of five british soldiers, termed it as micrococcus. In , the Danish veterinarian Bernard Lauritz Frederik Bang isolated microorganisms from cattle, termed it as Bacillus abortus In , Wright and Smith described brucellosis as a zoonotic disease, after detecting specific antibodies of Brucella melitensis in human and animal serum.

In , Bernhard Bang and Danish veterinarian isolated Brucella abortus as the agent and the additional name Bang's disease was assigned. In modern usage "Bang's disease" is often shortened to just " bangs " when ranchers discuss the disease or vaccine.

In , Maltese doctor and archaeologist Sir Temi Zammit identified unpasteurized milk as the major source of the pathogen and it has since become known as Malta Fever or Deni Rqiq locally.

In cattle this disease is also known as contagious abortion or infectious abortion. The popular name undulant fever originates from the characteristic undulance or wave-like nature of the fever which rises and falls over weeks in untreated patients. In the 20th Century, this name, along with " Brucellosis " after Brucella , named for Dr Bruce , gradually replaced the 19th Century names "Mediterranean fever" and "Malta fever".

In , neurologists in Saudi Arabia discovered "Neurobrucellosis", a neurological involvement in Brucellosis. Infez Med. PMID On the application of the serum test to the differential diagnosis of typhoid fever and Malta fever.

Cookies help us deliver our services. By using our services, you agree to our use of cookies. Namespaces Home Page Discussion. Views Read View source View history Help. Next, in , the first trial of chlor-tetracycline Aureomycin was made in Mexico, initially combined with sulfadiazine, but soon by itself. This drug had the practical advantage over streptomycin of oral administration and lack of oto-toxicity.

Some cases who had failed streptomycin — sulfadiazine were cured As with previous drugs, in cases in which Aureomycin failed were reported Spink et al. The last drugs to be cited in this brief review are chloramphenicol Chloromycetin and oxy-tetracycline Terramycin. Harris found the former drug to be equally effective and better tolerated than Aureomycin In , also initially in Mexico, oxy-tetracycline Terramycin was introduced. Bruce, D: Note on the discovery of a micro-organism in Malta fever.

Practitioner, , Lancet, , Amer J Med Sci. JAMA, , Bull J Hopkins Hosp. Ann Intern Med, , See p. Spink, WW: Pathogenesis of human Brucellosis with respect to prevention and treatment. Ann Intern Med. Angle, FE: Treatment of acute Brucellosis undulant fever. Dalrymple-Champneys, W: Undulant Fever.

With special reference to its clinical aspects in England and Wales. Neumann, CZ: On the treatment of undulant fever with Fouadin. Blumgart, HL: Recovery of a patient with undulant fever treated with sulfanilamide. In Malta, failure to control rogue flocks and small flocks kept for family use led to an epidemic caused by the sale of cheeselets small cheeses. In , nearly a century after Zammit's discovery, Malta was finally free of brucellosis.

Abstract The disease we now know as brucellosis was first discovered in the s in Malta. Publication types Historical Article.